Entrepreneurship is the buzzword of today. Everybody wants to be an entrepreneur. Even as a university student you can obtain a special status as student-entrepreneur. Great! We need more companies who create value and who drive our economy. But how do you organize your idea or research into a business plan? In this lecture I will give an overview of new businesses emerging in the nanobio field. Hereby, I will share my experience with setting up a nanobiotech company (still in progress!) and highlight the tools that have helped me structure my approach!