Selection of novel ligands and their application in biomonitoring
Elke Boschke
TU Dresden

Dec. 8, 2011, 1 p.m.


Fast monitoring of the microbiological state is highly important, not only in medical diag\ADnostics, but also in the pharmaceutical and food industries. But there are constitutional problems with detection of contaminants and pathogens respectively. These drawbacks are outlined and some new approaches in microbiology are introduced in particular the use of Biomagnetic Separation for pre-enrichment and Surface Plasmon Resonance Spectroscopy as a tool for germ detection. In that context selection of novel ligands \u2013 nucleic acid- and peptide-aptamers \u2013 is required to replace cost-intensive and unstable antibodies.



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Selection of novel ligands and their application in biomonitoring
Elke Boschke
TU Dresden

Dec. 8, 2011, 1 p.m.


Fast monitoring of the microbiological state is highly important, not only in medical diag\ADnostics, but also in the pharmaceutical and food industries. But there are constitutional problems with detection of contaminants and pathogens respectively. These drawbacks are outlined and some new approaches in microbiology are introduced in particular the use of Biomagnetic Separation for pre-enrichment and Surface Plasmon Resonance Spectroscopy as a tool for germ detection. In that context selection of novel ligands \u2013 nucleic acid- and peptide-aptamers \u2013 is required to replace cost-intensive and unstable antibodies.



Share